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(+)-DHMEQ

(+)-DHMEQ

Item no.	HY-14645A-10mM
Manufacturer	MedChem Express
CASRN	287194-41-6
Amount	10 mM/1 mL
Quantity options	10 mM/1 mL 10 mg 25 mg 2 mg 5 mg
Category	Neuroscience Metabolism Diabetes Glucose Homeostasis Targets for Rodent Neurosciences Aging & Neurological Disorders Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	99.33
Citations	[1]Niitsu Y, et al. Chemoenzymatic synthesis of (2R,3R,4R)-dehydroxymethylepoxyquinomicin (DHMEQ), a newactivator of antioxidant transcription factor Nrf2. Org Biomol Chem. 2011 Jun 21;9(12):4635-41.
Smiles	O=C(NC([C@@H](O)[C@@]1([H])O[C@@]21[H])=CC2=O)C3=CC=CC=C3O
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	(1R,2R,6R)-Dehydroxymethylepoxyquinomicin,(1R,2R,6R)-DHMEQ
Shipping Condition	Room temperature
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	COVID-19-immunoregulation
Manufacturer - Targets	Keap1-Nrf2
Shipping Temperature	Room Temperature
Storage Conditions	-20°C, 3 years; 4°C, 2 years (Powder)
Molecular Weight	261.23
Product Description	(+)-DHMEQ is an activator of antioxidant transcription factor Nrf2. (+)-DHMEQ is the enantiomer of (-)-DHMEQ. (-)-DHMEQ inhibits NF-kB than its enantiomer (+)-DHMEQ.
Manufacturer - Research Area	Inflammation/Immunology
Solubility	DMSO: 100 mg/mL (ultrasonic)
Manufacturer - Pathway	NF-κB
Clinical information	No Development Reported

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HY-14645A-10mM-safety-datasheet.pdf