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Fluvastatin (sodium)

Fluvastatin (sodium)

Item no.	HY-14664A-50mg
Manufacturer	MedChem Express
CASRN	93957-55-2
Amount	50 mg
Quantity options	100 mg 10 mM/1 mL 50 mg
Category	Oncology Metabolism Cholesterol & Lipid Metabolism Inhibitors & Compound Libraries Small Molecules By Organ Colorectal Cancer Testicular & Prostate Cancer Hepatic Cancer
Type	Inhibitors
Specific against	other
Purity	99.94
Citations	[1]Makabe S, et al. Fluvastatin protects vascular smooth muscle cells against oxidative stress through the Nrf2-dependent antioxidant pathway. Atherosclerosis. 2010 Dec;213(2):377-84.\|[2]Wu Zhang, et al. Fluvastatin, a lipophilic statin, induces apoptosis in human hepatocellular carcinoma cells through mitochondria-operated pathway. Indian J Exp Biol. 2010 Dec;48(12):1167-74. Front Bioeng Biotechnol. 2022 Mar 17;10:826093.\|Mol Med Rep. 2018 Mar;17(3):3944-3950.\|Pathogens. 2021, 10(3), 283.\|Phytother Res. 2025 Feb 13.\|Biochem Biophys Res Commun. 2020 Feb 19;522(4):862-868.\|Biomed Pharmacother. 2024 Apr 30:175:116644.\|bioRxiv. 2024 October 04.\|Cell Prolif. 2021 Jan;54(1):e12953.\|Cell Rep Med. 2024 May 29:101592.\|Chem Eng J. 1 January 2023, 138972.\|Front Cell Dev Biol. 2020 May 28;8:404.\|Front Oncol. 10 May 2021.\|Front Oncol. 2021 May 10;11:595285.\|Pharmacol Res. 2023 Mar 10;106724.\|PLoS Biol.2024 May 28;22(5):e3002621.\|Proteomics. 2023 May 4;e2300041.
Smiles	O=C(O[Na])C[C@H](O)C[C@H](O)/C=C/C(N1C(C)C)=C(C2=CC=C(F)C=C2)C3=C1C=CC=C3
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	XU 62-320
Shipping Condition	Room temperature
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	COVID-19-immunoregulation
Manufacturer - Targets	Autophagy; Ferroptosis; HMG-CoA Reductase (HMGCR)
Shipping Temperature	Room Temperature
Storage Conditions	4°C (Powder, sealed storage, away from moisture)
Molecular Weight	433.45
Product Description	Fluvastatin sodium (XU 62320) is a first fully synthetic, competitive HMG-CoA reductase inhibitor with an IC50 of 8 nM. Fluvastatin sodium protects vascular smooth muscle cells against oxidative stress through the Nrf2-dependent antioxidant pathway[1][2][3].
Manufacturer - Research Area	Cardiovascular Disease; Cancer
Solubility	DMSO: 50 mg/mL (ultrasonic)\|H2O: 50 mg/mL (ultrasonic)
Manufacturer - Pathway	Apoptosis; Autophagy; Metabolic Enzyme/Protease
Clinical information	Launched

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HY-14664A-50mg-safety-datasheet.pdf