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Palifosfamide

Palifosfamide

Item no.	HY-14798-50mg
Manufacturer	MedChem Express
CASRN	31645-39-3
Amount	50 mg
Quantity options	10 mM/1 mL 10 mg 50 mg 5 mg
Category	Food Safety Allergenes Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	99.11
Citations	[1]Hingorani P, et al. Preclinical activity of palifosfamide lysine (ZIO-201) in pediatric sarcomas including oxazaphosphorine-resistant osteosarcoma. Cancer Chemother Pharmacol. 2009 Sep;64(4):733-40.\|[2]Jones B, et al. Anticancer activity of stabilized palifosfamide in vivo: schedule effects, oral bioavailability, and enhanced activity with docetaxel and doxorubicin. Anticancer Drugs. 2012 Feb;23(2):173-84.
Smiles	O=P(NCCCl)(NCCCl)O
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	Isophosphoramide mustard,IPM,ZIO-201
Shipping Condition	Cool pack
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	Cancer-programmed cell death
Manufacturer - Targets	DNA Alkylator/Crosslinker; Drug Metabolite
Shipping Temperature	Blue Ice
Storage Conditions	-20°C (Powder, protect from light, stored under nitrogen)
Molecular Weight	221.02
Product Description	Palifosfamide is a novel DNA alkylator and the active metabolite of ifosfamide, with antitumor activity.
Manufacturer - Research Area	Cancer
Solubility	DMSO: 125 mg/mL (ultrasonic)\|H2O: 14.29 mg/mL (ultrasonic)
Manufacturer - Pathway	Cell Cycle/DNA Damage; Metabolic Enzyme/Protease
Clinical information	Phase 2

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HY-14798-50mg-safety-datasheet.pdf