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AMG 487

AMG 487

Manufacturer	MedChem Express
Category	Oncology Neuroscience Neural Lineage Markers Neuroinflammation Inhibitors & Compound Libraries Small Molecules By Organ Lung Cancer Stem Cell Markers
Type	Inhibitors
Specific against	other
Amount	5 mg
Item no.	HY-15319-5mg
Targets	CXCR
CASRN	473719-41-4
eClass 6.1	30220300
eClass 9.0	32160605
Available
Product Description	AMG 487 is an orally active and selective antagonist of CXC chemokine receptor 3 (CXCR3) which inhibits the binding of CXCL10 and CXCL11 to CXCR3 with IC50s of 8.0 and 8.2 nM, respectively[1].
StorageTemperature	-20°C, 3 years; 4°C, 2 years (Powder)
Shipping	Room Temperature
Manufacturers Applications	Cancer-programmed cell death
MolecularWeight	603.59
Clinical_Information	No Development Reported
Manufacturers Research_Area	Cancer; Inflammation/Immunology; Endocrinology
Solubility	DMSO : ≥ 41 mg/mL
Manufacturers Target	CXCR
Isoform	CXCR3
Pathway	GPCR/G Protein; Immunology/Inflammation
Manufacturers Product type	Reference compound

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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HY-15319-5mg-safety-datasheet.pdf