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GDC-0834 (S-enantiomer)

GDC-0834 (S-enantiomer)

Item no.	HY-15427B-10mM
Manufacturer	MedChem Express
CASRN	1133432-50-4
Amount	10 mM/1 mL
Quantity options	100 mg 10 mM/1 mL 10 mg 25 mg 2 mg 50 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	98.03
Citations	[1]Young WB, et al. Potent and selective Bruton's tyrosine kinase inhibitors: discovery of GDC-0834. Bioorg Med Chem Lett. 2015 Mar 15;25(6):1333-7
Smiles	CC1=C(C(N=C2NC3=CC=C([C@@H]4N(C)CCN(C)C4=O)C=C3)=CN(C)C2=O)C=CC=C1NC(C5=CC6=C(CCCC6)S5)=O
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	1133432-50-4
Shipping Condition	Room temperature
Available
Manufacturer - Type	Reference compound
Manufacturer - Targets	Btk
Shipping Temperature	Room Temperature
Storage Conditions	-20°C, 3 years; 4°C, 2 years (Powder)
Molecular Weight	596.74
Product Description	GDC-0834 (S-enantiomer) is the S-enantiomer of GDC-0834. GDC-0834 is a potent and selective BTK inhibitor.
Manufacturer - Research Area	Others
Solubility	DMSO: 100 mg/mL (ultrasonic)
Manufacturer - Pathway	Protein Tyrosine Kinase/RTK
Clinical information	No Development Reported

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HY-15427B-10mM-safety-datasheet.pdf