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(S)-Gossypol (acetic acid)

(S)-Gossypol (acetic acid)

Item no.	HY-15464D-50mg
Manufacturer	MedChem Express
CASRN	1189561-66-7
Amount	50 mg
Quantity options	100 mg 10mM/1mL 10 mg 50 mg 5 mg
Category	Oncology Inhibitors & Compound Libraries Small Molecules By Organ Skin Cancer Colorectal Cancer Lymphatic System Cancer
Type	Inhibitors
Clone	N/A
Specific against	other
Purity	98.39
Formula	C32H34O10
Citations	Patent. US20220162561A1. Cancer Lett. 2019 Oct 1;461:31-43. Clin Transl Med. 2021 Jun;11(6):e467. Patent. US20220162561A1. Microb Pathog. 2024 Sep 21:106960. Transbound Emerg Dis. 2023 Nov 11. Nat Commun. 2023 Jun 10;14(1):3445. [1]Oliver CL, et al. In vitro effects of the BH3 mimetic, (-)-Gossypol, on head and neck squamous cell carcinoma cells. Clin Cancer Res. 2004 Nov 15;10(22):7757-63.
Smiles	OC1=C2C(C=O)=C(O)C(O)=C(C(C)C)C2=CC(C)=[C@@]1[C@@]3=C(C)C=C4C(C(C)C)=C(O)C(O)=C(C=O)C4=C3O.CC(O)=O
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	(S)-(+)-Gossypol acetic acid
Shipping Condition	Cool pack
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	Cancer-programmed cell death
Manufacturer - Targets	Bcl-2 Family
Shipping Temperature	Blue Ice
Storage Conditions	-20°C (Powder, protect from light, stored under nitrogen)
Molecular Weight	578.61
Product Description	(S)-Gossypol is the isomer of a natural product Gossypol. (S)-Gossypol binds to the BH3-binding groove of Bcl-xL and Bcl-2 proteins with high affinity.
Manufacturer - Research Area	Cancer
Solubility	DMSO : 50 mg/mL (ultrasonic)
Manufacturer - Pathway	Apoptosis
Isoform	Bcl-2; Bcl-xL
Clinical information	Phase 3

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

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HY-15464D-50mg-safety-datasheet.pdf