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KN-92 (hydrochloride)

KN-92 (hydrochloride)

Item no.	HY-15517B-50mg
Manufacturer	MedChem Express
CASRN	1431698-47-3
Amount	50 mg
Quantity options	100 mg 10mM/1mL 10 mg 1 mg 25 mg 2 mg 50 mg 5 mg
Category	Oncology Food Safety Histamines Neuroscience Metabolism Cholesterol & Lipid Metabolism Molecular Targets for Neuroscience Inhibitors & Compound Libraries Small Molecules By Organ Colorectal Cancer
Type	Inhibitors
Specific against	other
Purity	99.99
Formula	C24H26Cl2N2O3S
Citations	[1]Smyth JT, et al. Inhibition of the inositol trisphosphate receptor of mouse eggs and A7r5 cells by KN-93 via a mechanism unrelated to Ca2+/calmodulin-dependent protein kinase II antagonism. J Biol Chem. 2002;277(38):35061-35070. [2]An P, et al. KN-93, a specific inhibitor of CaMKII inhibits human hepatic stellate cell proliferation in vitro. World J Gastroenterol. 2007;13(9):1445-1448.
Smiles	O=S(C1=CC=C(OC)C=C1)(NC2=CC=CC=C2CN(C/C=C/C3=CC=C(Cl)C=C3)C)=O.[H]Cl
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	1431698-47-3
Shipping Condition	Room temperature
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	Cancer-Kinase/protease
Manufacturer - Targets	CaMK
Shipping Temperature	Room Temperature
Storage Conditions	4°C (Powder, sealed storage, away from moisture)
Molecular Weight	493.45
Product Description	KN-92 hydrochloride is an inactive derivative of KN-93, without CaM kinase inhibitory activity. KN-92 hydrochloride is intended to be used as a control compound in studies designed to elucidate the antagonist activities of KN-93[1][2].
Manufacturer - Research Area	Cancer
Solubility	DMSO : ≥ 50 mg/mL\|H2O : < 0.1 mg/mL (ultrasonic; warming; heat to 60°C)
Manufacturer - Pathway	Neuronal Signaling
Clinical information	No Development Reported

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HY-15517B-50mg-safety-datasheet.pdf