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kb NB 142-70

kb NB 142-70

Item no.	HY-15528-10mg
Manufacturer	MedChem Express
CASRN	1233533-04-4
Amount	10 mg
Quantity options	10 mM/1 mL 10 mg 25 mg 50 mg 5 mg
Category	Oncology Inhibitors & Compound Libraries Small Molecules By Organ Testicular & Prostate Cancer
Type	Inhibitors
Specific against	other
Purity	98.08
Citations	[1]Lavalle CR, et al. Novel protein kinase D inhibitors cause potent arrest in prostate cancer cell growth and motility. BMC Chem Biol. 2010 May 5;10:5.\|[2]James Sinnett-Smith, et al. Protein kinase D1 mediates class IIa histone deacetylase phosphorylation and nuclear extrusion in intestinal epithelial cells: role in mitogenic signaling. Am J Physiol Cell Physiol. 2014 May 15; 306(10): C961-C971.
Smiles	O=C1NCCSC2=C1SC3=CC=C(O)C=C32
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	1233533-04-4
Shipping Condition	Room temperature
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	Cancer-Kinase/protease
Manufacturer - Targets	PKD
Shipping Temperature	Room Temperature
Storage Conditions	-20°C, 3 years; 4°C, 2 years (Powder)
Molecular Weight	251.32
Product Description	kb NB 142-70 is a potent PKD inhibitor, with IC50s of 28.3, 58.7 and 53.2 nM for PKD1, PKD2, and PKD3, respectively. kb NB 142-70 also has antitumor activity.
Manufacturer - Research Area	Cancer
Solubility	DMSO: 46.67 mg/mL (ultrasonic)
Manufacturer - Pathway	Apoptosis
Isoform	PKD1; PKD2; PKD3
Clinical information	No Development Reported

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HY-15528-10mg-safety-datasheet.pdf