FH535

Item no.	HY-15721-10mg
Manufacturer	MedChem Express
CASRN	108409-83-2
Amount	10 mg
Quantity options	100 mg 10 mM/1 mL 10 mg 50 mg 5 mg
Category	Food Safety Allergenes Neuroscience Neuroinflammation Metabolism Diabetes Cholesterol & Lipid Metabolism Neural Signaling Enzymes Other Fatty Acid Enzymes Inhibitors & Compound Libraries Small Molecules Other Lipid\Cholesterol Metabolism Modulators
Type	Inhibitors
Specific against	other
Purity	99.88
Citations	[1]Handeli S, et al. A small-molecule inhibitor of Tcf/beta-catenin signaling down-regulates PPARgamma and PPARdelta activities. Mol Cancer Ther. 2008 Mar;7(3):521-9.\|[2]Wu MY, et al. FH535 inhibited metastasis and growth of pancreatic cancer cells. Onco Targets Ther. 2015 Jul 6;8:1651-70.\|[3]Liu L, et al. FH535, a β-catenin pathway inhibitor, represses pancreatic cancer xenograft growth and angiogenesis. Oncotarget. 2016 Jul 26;7(30):47145-47162.
Smiles	O=S(C1=CC(Cl)=CC=C1Cl)(NC2=CC=C([N+]([O-])=O)C=C2C)=O
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	108409-83-2
Shipping Condition	Room temperature
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	Cancer-programmed cell death
Manufacturer - Targets	PPAR; Wnt; β-catenin
Shipping Temperature	Room Temperature
Storage Conditions	-20°C, 3 years; 4°C, 2 years (Powder)
Molecular Weight	361.20
Product Description	FH535 is an inhibitor of Wnt/β-catenin and PPAR with anti-tumor activities[1].
Manufacturer - Research Area	Cancer
Solubility	DMSO: 33.33 mg/mL (ultrasonic)
Manufacturer - Pathway	Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; Stem Cell/Wnt; Vitamin D Related/Nuclear Receptor
Isoform	PPAR
Clinical information	No Development Reported

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HY-15721-10mg-safety-datasheet.pdf