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TCS-PIM-1-4a

TCS-PIM-1-4a

Item no.	HY-16576-5mg
Manufacturer	MedChem Express
CASRN	327033-36-3
Amount	5 mg
Quantity options	100 mg 10 mM x 1 mL 10 mg 50 mg 5 mg
Category	Oncology Neuroscience Neural Signaling Inhibitors & Compound Libraries Small Molecules By Organ Skin Cancer Heart & Blood Cancer Lymphatic System Cancer
Type	Inhibitors
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	327033-36-3
Available
Storage Conditions	Powder -20°C 3 years, 4°C 2 years; In solvent -80°C 6 months, -20°C 1 month
Molecular Weight	273.23
Product Description	TCS-PIM-1-4a (SMI-4a) is a pan-Pim kinases inhibitor that blocks mTORC1 activity via activation of AMPK. TCS-PIM-1-4a kills a wide range of both myeloid and lymphoid cell lines (IC50 values ranging from 0.8 μM to 40 μM).
Manufacturer - Research Area	Cancer
Solubility	DMSO : ≥ 100 mg/mL (365.99 mM)
Manufacturer - Pathway	JAK/STAT Signaling; Apoptosis
Clinical information	No Development Reported

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