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Miglustat (hydrochloride)

Miglustat (hydrochloride)

Item no.	HY-17020A-10mM
Manufacturer	MedChem Express
CASRN	210110-90-0
Amount	10 mM/1 mL
Quantity options	100 mg 10 mM/1 mL 10 mg 1 mg 25 mg 50 mg 5 mg
Category	Neuroscience Metabolism Cholesterol & Lipid Metabolism Molecular Targets for Neuroscience Enzymes Other Fatty Acid Enzymes Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	98.0
Citations	[1]Maria Cristina Dechecchi, et al. Anti-inflammatory effect of miglustat in bronchial epithelial cells. J Cyst Fibros. 2008 Nov;7(6):555-65. \|[2]G D'Arcangelo, et al. Miglustat Reverts the Impairment of Synaptic Plasticity in a Mouse Model of NPC Disease. Neural Plast. 2016:2016:3830424. Cell. 2019 Dec 12;179(7):1483-1498.e22.\|Cell Rep. 2022 Jul 5;40(1):111049.\|J Virol. 2025 Feb 13:e0001825.\|Nat Commun. 2024 Aug 14;15(1):6970.\|Preprints. 2023 Dec 20.
Smiles	O[C@H]1[C@H](O)[C@@H](CO)N(CCCC)C[C@@H]1O.[H]Cl
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	N-Butyldeoxynojirimycin (hydrochloride),NB-DNJ (hydrochloride),OGT 918 (hydrochloride)
Shipping Condition	Cool pack
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	Neuroscience-Neuromodulation
Manufacturer - Targets	Glucosylceramide Synthase (GCS)
Shipping Temperature	Blue Ice
Storage Conditions	-20°C (Powder, stored under nitrogen)
Molecular Weight	255.74
Product Description	Miglustat (N-Butyldeoxynojirimycin) hydrochloride is an orally active and reversible ceramide glucosyltransferase inhibitor. Miglustat hydrochloride can be used for the research of type I gaucher disease[1][2].
Manufacturer - Research Area	Inflammation/Immunology; Neurological Disease
Solubility	DMSO: 65 mg/mL (ultrasonic)\|H2O: ≥ 34 mg/mL
Manufacturer - Pathway	Neuronal Signaling
Clinical information	Launched

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HY-17020A-10mM-safety-datasheet.pdf