Comparison

Gemcitabine European Partner

Item no. HY-17026-500mg
Manufacturer MedChem Express
CASRN 95058-81-4
Amount 500 mg
Quantity options 100 mg 10 mM/1 mL 1 g 200 mg 500 mg 5 g
Category
Type Inhibitors
Specific against other
Purity 99.94
Citations [1]Wang H, et al. Enhanced efficacy of Gemcitabine by indole-3-carbinol in pancreatic cell lines: the role of human equilibrativenucleoside transporter 1. Anticancer Res. 2011 Oct;31(10):3171-80.|[2]Yip-Schneider MT, et al. Dimethylaminoparthenolide and Gemcitabine: a survival study using a genetically engineered mouse model of pancreatic cancer. BMC Cancer. 2013 Apr 17;13:194.|[3]Gagnadoux F, et al. Safety of pulmonary administration of gemcitabine in rats. J Aerosol Med. 2005 Summer;18(2):198-206|[4]Yusheng Cai, et al. Elimination of senescent cells by β-galactosidase-targeted prodrug attenuates inflammation and restores physical function in aged mice. Cell Res. 2020 Jul;30(7):574-589.
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Smiles NC(C=CN1[C@H]2C(F)(F)[C@H](O)[C@@H](CO)O2)=NC1=O
ECLASS 10.1 32160490
ECLASS 11.0 32160490
UNSPSC 12000000
Alias LY 188011
Shipping Condition Room temperature
Available
Manufacturer - Type
Reference compound
Manufacturer - Applications
Cancer-programmed cell death
Manufacturer - Category
Reference compound / Active compounds; API
Manufacturer - Targets
Apoptosis; Autophagy; DNA/RNA Synthesis; Nucleoside Antimetabolite/Analog
Manufacturer - HS Code
H302, H315, H319, H335
Shipping Temperature
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Molecular Weight
263.2
Product Description
Gemcitabine (LY 188011) is a pyrimidine nucleoside analog antimetabolite and an antineoplastic agent. Gemcitabine inhibits DNA synthesis and repair, resulting in autophagyand apoptosis[1][2].
Manufacturer - Research Area
Cancer
Solubility
DMSO : 200 mg/mL (ultrasonic)|Ethanol : 12.5 mg/mL (ultrasonic)|H2O : 6.25 mg/mL (ultrasonic; warming)
Manufacturer - Pathway
Apoptosis; Autophagy; Cell Cycle/DNA Damage
Clinical information
Launched
UNSPSC Code
12352005
Precautionary
H302, H315, H319, H335

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 500 mg
Available: In stock
available

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