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Dimethyl fumarate

Dimethyl fumarate

Manufacturer	MedChem Express
Category	Food Safety Banned Food Additives Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Amount	500 mg
Item no.	HY-17363-500mg
Targets	KEAP1
CASRN	624-49-7
eClass 6.1	30220300
eClass 9.0	32160605
Available
Product Description	Dimethyl fumarate (DMF) is an orally active and brain-penetrant Nrf2 activator and induces upregulation of antioxidant gene expression. Dimethyl fumarate induces necroptosis in colon cancer cells through GSH depletion/ROS increase/MAPKs activation pathway, and also induces cell autophagy. Dimethyl fumarate can be used for multiple sclerosis research[1][2].
StorageTemperature	-20°C, 3 years; 4°C, 2 years (Powder)
Shipping	Room Temperature
Manufacturers Applications	COVID-19-immunoregulation
MolecularWeight	144.13
Clinical_Information	Launched
Manufacturers Research_Area	Cancer; Infection; Inflammation/Immunology; Neurological Disease
Solubility	DMSO : 41.67 mg/mL (ultrasonic)
Pathway	Anti-infection; Autophagy; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Manufacturers Product type	Natural Products

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HY-17363-500mg-safety-datasheet.pdf