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Rosuvastatin (Calcium)

Rosuvastatin (Calcium)

Manufacturer	MedChem Express
Category	Oncology Neuroscience Neuroinflammation Metabolism Diabetes Glucose Homeostasis Cholesterol & Lipid Metabolism Neural Adhesion Molecules Inhibitors & Compound Libraries Small Molecules By Organ Bladder Cancer
Type	Inhibitors
Specific against	other
Clone	N/A
Amount	10 mg
Item no.	HY-17504-10mg
Targets	HMGCR
CASRN	147098-20-2
eClass 6.1	30220300
eClass 9.0	32160605
Available
Product Description	Rosuvastatin Calcium is a competitive HMG-CoA reductase (HMGCR) inhibitor, with an IC50 of 11 nM. Rosuvastatin Calcium potently blocks hERG current with an IC50 of 195 nM[2]. Rosuvastatin Calcium reduces the expression of the mature hERG and the interaction of heat shock protein 70 (Hsp70) with the hERG protein. Rosuvastatin Calcium effectively lowers low-density lipoprotein (LDL) cholesterol, triglycerides, and C-reactive protein levels[1][2][3].
StorageTemperature	4°C (Powder, sealed storage, away from moisture)
Shipping	Room Temperature
Manufacturers Applications	Cancer-programmed cell death
MolecularWeight	500.57
Clinical_Information	Launched
Manufacturers Research_Area	Metabolic Disease; Cardiovascular Disease; Cancer
Solubility	DMSO : 25 mg/mL (ultrasonic)\|H2O : 1 mg/mL (ultrasonic)
Pathway	Anti-infection; Autophagy; Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease
Manufacturers Product type	Reference compound

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

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HY-17504-10mg-safety-datasheet.pdf