« Back
Home /
Rosuvastatin-d6 (sodium)

Rosuvastatin-d6 (sodium)

Item no.	HY-17504BS1-1mg
Manufacturer	MedChem Express
CASRN	2070009-41-3
Amount	1 mg
Quantity options	1 mg 500 ug 5 mg
Category	Metabolism Cholesterol & Lipid Metabolism Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	98.60
Smiles	O=C(O[Na])C[C@H](O)C[C@H](O)/C=C/C1=C(C(C([2H])([2H])[2H])C([2H])([2H])[2H])N=C(N(C)S(C)(=O)=O)N=C1C2=CC=C(C=C2)F
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Shipping Condition	Cool pack
Available
Manufacturer - Type	Isotope-Labeled Compounds
Manufacturer - Applications	Metabolism-sugar/lipid metabolism
Manufacturer - Category	Isotope-Labeled Compounds; Reference compound / Active compounds
Manufacturer - Targets	Autophagy; HMG-CoA Reductase (HMGCR)
Manufacturer - HS Code	H302
Shipping Temperature	Blue Ice
Storage Conditions	-20°C (Powder, sealed storage, away from moisture)
Molecular Weight	509.56
Product Description	Rosuvastatin-d6 sodium is deuterium labeled Rosuvastatin sodium (HY-17504B). Rosuvastatin Sodium is a competitive HMG-CoA reductase (HMGCR) inhibitor, with an IC50 of 11 nM. Rosuvastatin Sodium potently blocks hERG current with an IC50 of 195 nM. Rosuvastatin Sodium reduces the expression of the mature hERG and the interaction of heat shock protein 70 (Hsp70) with the hERG protein. Rosuvastatin Sodium effectively lowers low-density lipoprotein (LDL) cholesterol, triglycerides, and C-reactive protein levels.
Manufacturer - Research Area	Metabolic Disease; Cardiovascular Disease
Solubility	10 mM in DMSO
Manufacturer - Pathway	Autophagy; Metabolic Enzyme/Protease
Clinical information	No Development Reported
UNSPSC Code	12352005
Precautionary	H302

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.