Comparison

PLpro inhibitor European Partner

Item no. HY-17542-50mg
Manufacturer MedChem Express
CASRN 1093070-14-4
Amount 50 mg
Quantity options 100 mg 10 mM/1 mL 10 mg 1 mg 50 mg 5 mg
Category
Type Inhibitors
Specific against other
Purity 99.88
Citations [1]Ratia, K., et al., A noncovalent class of papain-like protease/deubiquitinase inhibitors blocks SARS virus replication. Proc Natl Acad Sci U S A, 2008. 105(42): p. 16119-24.|[2]http://www.google.com/patents/WO2010022355A1cl=en|[3]Brendan T Freitas, et al. Characterization and Noncovalent Inhibition of the Deubiquitinase and deISGylase Activity of SARS-CoV-2 Papain-Like Protease. ACS Infect Dis. 2020 May 19.
Smiles O=C(C1=CC(NC(C)=O)=CC=C1C)N[C@H](C)C2=C(C=CC=C3)C3=CC=C2
ECLASS 10.1 32160490
ECLASS 11.0 32160490
UNSPSC 12000000
Alias 1093070-14-4
Similar products 1093070-14-4
Shipping Condition Room temperature
Available
Manufacturer - Type
Reference compound
Manufacturer - Applications
COVID-19-anti-virus
Manufacturer - Targets
SARS-CoV
Shipping Temperature
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Molecular Weight
346.42
Product Description
PLpro inhibitor is a potent inhibitor of papain-like protease (PLpro) with an IC50 of 2.6 μM[1]. PLpro inhibitor inhibits SARS-CoV-2 PLpro with an IC50 of 5.0 μM and an EC50 of 21.0 μM[2].
Manufacturer - Research Area
Infection
Solubility
DMSO: 100 mg/mL (ultrasonic)
Manufacturer - Pathway
Anti-infection
Clinical information
No Development Reported

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 50 mg
Available: In stock
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