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ALW-II-41-27

ALW-II-41-27

Item no.	HY-18007-5mg
Manufacturer	MedChem Express
CASRN	1186206-79-0
Amount	5 mg
Quantity options	10 mM/1 mL 10 mg 1 mg 50 mg 5 mg
Category	Oncology Neuroscience Neural Lineage Markers Aging & Neurological Disorders Neural Development Neural Adhesion Molecules Inhibitors & Compound Libraries Small Molecules By Organ Colorectal Cancer Heart & Blood Cancer Stem Cell Markers
Type	Inhibitors
Specific against	other
Purity	99.70
Formula	C32H32F3N5O2S
Citations	[1]Choi, et al. Discovery and structural analysis of Eph receptor tyrosine kinase inhibitors. Bioorganic & Medicinal Chemistry Letters (2009), 19(15), 4467-4470. [2]Song W, et al. Targeting EphA2 impairs cell cycle progression and growth of basal-like/triple-negative breast cancers. Oncogene. 2017 Jun 5.
Smiles	CC1=C(NC(C2=CC(C3=CC=CS3)=CN=C2)=O)C=C(C(NC4=CC=C(CN5CCN(CC)CC5)C(C(F)(F)F)=C4)=O)C=C1
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	Eph receptor tyrosine kinase inhibitor
Shipping condition	Room temperature
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	Cancer-Kinase/protease
Manufacturer - Targets	Ephrin Receptor
Shipping Temperature	Room Temperature
Storage Conditions	-20°C, 3 years; 4°C, 2 years (Powder)
Molecular Weight	607.69
Product Description	ALW-II-41-27 is a Eph family tyrosine kinase inhibitor with an IC50 of 11 nM for Eph2.
Manufacturer - Research Area	Cancer
Solubility	DMSO : ≥ 47 mg/mL
Manufacturer - Pathway	Protein Tyrosine Kinase/RTK
Clinical information	No Development Reported

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HY-18007-5mg-safety-datasheet.pdf