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NSC319726

NSC319726

Item no.	HY-18634-10mM
Manufacturer	MedChem Express
CASRN	71555-25-4
Amount	10 mM/1 mL
Quantity options	100 mg 10 mM/1 mL 10 mg 1 mg 25 mg 50 mg 5 mg
Category	Oncology Inhibitors & Compound Libraries Small Molecules By Organ Lung Cancer Bladder Cancer Breast Cancer
Type	Inhibitors
Specific against	other
Purity	99.60
Citations	[1]Yu X, et al. Allele-specific p53 mutant reactivation. Cancer Cell. 2012 May 15;21(5):614-25.
Smiles	C/C(C1=NC=CC=C1)=N\NC(N2CCC2)=S
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	ZMC1
Shipping Condition	Room temperature
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	Cancer-programmed cell death
Manufacturer - Targets	MDM-2/p53
Shipping Temperature	Room Temperature
Storage Conditions	-20°C, 3 years; 4°C, 2 years (Powder)
Molecular Weight	234.32
Product Description	NSC319726 (ZMC1) is a mutant p53R175 reactivator; inhibits growth of fibroblasts expressing the p53R175 mutation (IC50 = 8 nM); shows no inhibition for p53 wild-type cells.
Manufacturer - Research Area	Cancer
Solubility	DMSO: 31.25 mg/mL (ultrasonic)
Manufacturer - Pathway	Apoptosis
Clinical information	No Development Reported

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HY-18634-10mM-safety-datasheet.pdf