Comparison

O4I1 European Partner

Item no. HY-18771-10mg
Manufacturer MedChem Express
CASRN 175135-47-4
Amount 10 mg
Quantity options 100 mg 10 mM/1 mL 10 mg 200 mg 25 mg 50 mg 5 mg
Category
Type Inhibitors
Specific against other
Purity 98.05
Citations [1]Cheng X, et al. Identification of 2-[4-[(4-Methoxyphenyl)methoxy]-phenyl]acetonitrile and Derivatives as Potent Oct3/4 Inducers. J Med Chem. 2015 Jun 25;58(12):4976-4983.|[2]Mrowka, et al. Method for activating OCT4 for induction of pluripotent stem cell formation. From PCT Int. Appl. (2014), WO 2014000814 A1 20140103.
Smiles N#CCC1=CC=C(OCC2=CC=C(OC)C=C2)C=C1
ECLASS 10.1 32160490
ECLASS 11.0 32160490
UNSPSC 12000000
Alias 175135-47-4
Shipping Condition Room temperature
Available
Manufacturer - Type
Reference compound
Manufacturer - Targets
Oct3/4
Shipping Temperature
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Molecular Weight
253.30
Product Description
O4I1 is as a potent Oct3/4 inducer.Target: Oct3/4O4I1 enhances Oct3/4 gene expression, increases Oct3/4 protein levels, and promotes Oct3/4 mediated transcriptional activation. O4I1 activates Oct3/4 at the transcriptional and translational levels in diverse human cell lines. O4I1 promotes Oct3/4 expression in untransfected HEK293 cells quantified by qRT-PCR after 72 h of treatment. O4I1 is sufficient to enhance Oct3/4 overexpression 2-fold and 3-fold after 48 and 72 h of treatment, respectively.
Manufacturer - Research Area
Others
Solubility
DMSO: ≥ 38 mg/mL
Manufacturer - Pathway
Stem Cell/Wnt
Clinical information
No Development Reported

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 10 mg
Available: In stock
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