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ZD-1611

ZD-1611

Item no.	HY-19274-5mg
Manufacturer	MedChem Express
CASRN	186497-38-1
Amount	5 mg
Quantity options	100 mg 10 mg 1 ea 1 mg 20 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Citations	[1]Wilson C, et al. Pharmacological profile of ZD1611, a novel, orally active endothelin ETA receptor antagonist. J Pharmacol Exp Ther. 1999 Sep;290(3):1085-91. [2]Stenman E, et al. Cooperative effect of angiotensin AT(1) and endothelin ET(A) receptor antagonism limits the brain damage after ischemic stroke in rat. Eur J Pharmacol. 2007 Sep 10;570(1-3):142-8. Epub 2007 Jun 9.
Smiles	O=C(O)C(C)(C)CC1=CC=C(C2=NC=CC=C2S(=O)(NC3=NC=C(C)N=C3OC)=O)C=C1
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	186497-38-1
Shipping Condition	Room temperature
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	Metabolism-protein/nucleotide metabolism
Manufacturer - Targets	Endothelin Receptor
Shipping Temperature	Room temperature
Molecular Weight	456.51
Product Description	ZD-1611 is a potent, orally active, selective ETA receptor antagonist, used for the research of ischemic stroke.
Manufacturer - Research Area	Cardiovascular Disease; Endocrinology
Solubility	10 mM in DMSO
Manufacturer - Pathway	GPCR/G Protein
Isoform	ETA
Clinical information	Phase 1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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