NU2058

Item no.	HY-19316-100mg
Manufacturer	MedChem Express
CASRN	161058-83-9
Amount	100 mg
Quantity options	100 mg 10 mM/1 mL 10 mg 25 mg 50 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	99.66
Citations	[1]Rigas AC, et al. Therapeutic potential of CDK inhibitor NU2058 in androgen-independent prostate cancer. Oncogene. 2007 Dec 6;26(55):7611-7619.
Smiles	NC1=NC(OCC2CCCCC2)=C3NC=NC3=N1
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	O6-(Cyclohexylmethyl)guanine
Shipping Condition	Room temperature
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	Cancer-Kinase/protease
Manufacturer - Targets	CDK
Shipping Temperature	Room Temperature
Storage Conditions	-20°C, 3 years; 4°C, 2 years (Powder)
Molecular Weight	247.30
Product Description	NU2058 (O6-(Cyclohexylmethyl)guanine) is a potent, competitive and guanine-based CDK inhibitor with IC50s of 17 μM and 26 μM for CDK2 and CDK1. NU2058 has anti-cancer activity.
Manufacturer - Research Area	Cancer
Solubility	DMSO: ≥ 32 mg/mL
Manufacturer - Pathway	Cell Cycle/DNA Damage
Isoform	CDK1; CDK2
Clinical information	No Development Reported

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HY-19316-100mg-safety-datasheet.pdf