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Calcifediol (monohydrate)

Calcifediol (monohydrate)

Item no.	HY-32351A-5mg
Manufacturer	MedChem Express
CASRN	63283-36-3
Amount	5 mg
Quantity options	100 mg 10 mg 25 mg 50 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Clone	N/A
Specific against	other
Purity	99.89
Formula	C27H46O3
Citations	Sci Rep. 2022 Feb 22;12(1):3014. Front Pharmacol. 2020 Mar 31;11:200. Int Immunopharmacol. 2023 Jun 30;122:110558. Int J Mol Sci. 2017 Dec 19;18(12). pii: E2764. Nat Chem Biol. 2022 Aug 18. Proc Natl Acad Sci U S A. 2022 Apr 12;119(15):e2117004119. Ther Adv Endocrinol. 2020 Oct 20. Virol Sin. 2024 Aug 19:S1995-820X(24)00134-2. [1]Castoldi A, et al. Calcifediol-loaded liposomes for local treatment of pulmonary bacterial infections. Eur J Pharm Biopharm. 2016 Nov 22. [2]Wei Zheng, et al. Vitamin D-induced vitamin D receptor expression induces tamoxifen sensitivity in MCF-7 stem cells via suppression of Wnt/β-catenin signaling. Biosci Rep. 2018 Dec 7;38(6):BSR20180595.
Smiles	C=C(CC1)/C(C[C@H]1O)=C\C=C2[C@@]3([H])[C@@](CCC\2)(C)[C@@H]([C@H](C)CCCC(C)(C)O)CC3.O
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	25-hydroxy Vitamin D3 (monohydrate)
Shipping condition	Cool pack
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	COVID-19-immunoregulation
Manufacturer - Targets	Endogenous Metabolite; VD/VDR
Shipping Temperature	Blue Ice
Storage Conditions	-20°C (Powder, protect from light, stored under nitrogen)
Molecular Weight	418.65
Product Description	Calcifediol monohydrate (25-hydroxy Vitamin D3 monohydrate), is an effective VDR ligand and VD supplement. Calcifediol is a prohormone of the vitamin D endocrine system (VDES) and is hydroxylated in the liver to produce the active form, calcitriol. Calcifediol can rapidly increase serum VD levels[1][2][3].
Manufacturer - Research Area	Metabolic Disease
Solubility	DMSO : 50 mg/mL (ultrasonic)
Manufacturer - Pathway	Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor
Isoform	Human Endogenous Metabolite
Clinical information	Launched

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

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HY-32351A-5mg-safety-datasheet.pdf