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Zaurategrast ethyl ester

Zaurategrast ethyl ester

Item no.	HY-75385-10mg
Manufacturer	MedChem Express
CASRN	455264-30-9
Amount	10 mg
Quantity options	100 mg 10 mM/1 mL 10 mg 25 mg 50 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	99.21
Citations	[1]Chanteux H, et al. Cross-Species Differences in the Preclinical Pharmacokinetics of CT7758, an α4β1/α4β7 Integrin Antagonist. Drug Metab Dispos. 2015 Sep;43(9):1381-91.\|[2]Davenport RJ, et al. Alpha4-integrin antagonism--an effective approach for the treatment of inflammatory diseases? Drug Discov Today. 2007 Jul;12(13-14):569-76.
Smiles	O=C(OCC)[C@H](CC1=CC=C(NC2=NC=CC3=C2C=NC=C3)C=C1)NC4=C(Br)C(C45CCCCC5)=O
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	CDP323,UCB1184197
Shipping Condition	Room temperature
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	COVID-19-immunoregulation
Manufacturer - Targets	Integrin
Shipping Temperature	Room Temperature
Storage Conditions	-20°C, 3 years; 4°C, 2 years (Powder)
Molecular Weight	549.46
Product Description	Zaurategrast ethyl ester (CDP323), the ethyl ester proagent of CT7758[1], is a α4β1/α4β7 integrin antagonist used for the treatment of inflammatory and autoimmune disorders[2].
Manufacturer - Research Area	Inflammation/Immunology
Solubility	DMSO: 150 mg/mL (ultrasonic)
Manufacturer - Pathway	Cytoskeleton
Clinical information	Phase 2

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HY-75385-10mg-safety-datasheet.pdf