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Trifluridine

Trifluridine

Manufacturer	MedChem Express
Category	Oncology Metabolism Cholesterol & Lipid Metabolism Enzymes Other Fatty Acid Enzymes Inhibitors & Compound Libraries Small Molecules By Organ Breast Cancer
Type	Inhibitors
Specific against	other
Clone	N/A
Amount	100 mg
Item no.	HY-A0061-100mg
Targets	Thymidylate Synthase; HSV; Nucleoside Antimetabolite/Analog
CASRN	70-00-8
eClass 6.1	30220300
eClass 9.0	32160605
Available
Product Description	Trifluridine (Trifluorothymidine) is an irreversible and orally active thymidylate synthase inhibitor, and thereby suppressing DNA synthesis. Trifluridine is an antiviral molecule used for research of HSV, rhabdovirus and orthopoxvirus infection. Trifluridine induces cell apoptosis and autophagy. Trifluridine is also an anticancer agent used in studies of metastatic colorectal cancer, gastrointestinal tumors[1][2][3][4].
StorageTemperature	-20°C, 3 years; 4°C, 2 years (Powder)
Shipping	Room Temperature
Manufacturers Applications	Cancer-programmed cell death
MolecularWeight	296.20
Clinical_Information	Launched
Manufacturers Research_Area	Cancer
Solubility	DMSO : ≥ 100 mg/mL\|H2O : 33.33 mg/mL (ultrasonic; warming; heat to 60°C)
Manufacturers Target	Apoptosis; Autophagy; DNA/RNA Synthesis; HSV; Nucleoside Antimetabolite/Analog; Orthopoxvirus; Thymidylate Synthase
Isoform	HSV-1; HSV-2
Pathway	Anti-infection; Apoptosis; Autophagy; Cell Cycle/DNA Damage
Manufacturers Product type	Reference compound

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HY-A0061-100mg-safety-datasheet.pdf