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Fluphenazine (dihydrochloride)

Fluphenazine (dihydrochloride)

Manufacturer	MedChem Express
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Clone	N/A
Amount	100 mg
Item no.	HY-A0081-100mg
Targets	Dopamine Receptor
CASRN	146-56-5
eClass 6.1	30220300
eClass 9.0	32160605
Available
Product Description	Fluphenazine dihydrochloride is a potent, orally active phenothiazine-based dopamine receptor antagonist. Fluphenazine dihydrochloride blocks neuronal voltage-gated sodium channels. Fluphenazine dihydrochloride acts primarily through antagonism of postsynaptic dopamine-2 receptors in mesolimbic, nigrostriatal, and tuberoinfundibular neural pathways. Fluphenazine dihydrochloride can antagonize Methylphenidate-induced stereotyped gnawing and inhibit climbing behaviour in mice. Fluphenazine dihydrochloride can be used for researching psychosis and painful peripheral neuropathy associated with diabetes and has potential to inhibit SARS-CoV-2[1][2][3][4][6].
StorageTemperature	-20°C (Powder, stored under nitrogen)
Shipping	Blue Ice
Manufacturers Applications	Cancer-programmed cell death
MolecularWeight	510.44
Clinical_Information	Launched
Manufacturers Research_Area	Neurological Disease; Cancer
Solubility	DMSO : ≥ 38 mg/mL\|H2O : 100 mg/mL (ultrasonic)
Manufacturers Target	Dopamine Receptor; SARS-CoV; Sodium Channel
Pathway	Anti-infection; GPCR/G Protein; Membrane Transporter/Ion Channel; Neuronal Signaling
Manufacturers Product type	Reference compound

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HY-A0081-100mg-safety-datasheet.pdf