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Gentamicin (sulfate)

Gentamicin (sulfate)

Item no.	HY-A0276-1g
Manufacturer	MedChem Express
CASRN	1405-41-0
Amount	1 g
Quantity options	10 mMx1 mL 1 g 500 mg 5 g
Category	Food Safety Antibiotics Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Citations	[1]Xu W, et al. A rapid and sensitive method for kinetic study and activity assay of DNase I in vitro based on a GO-quenched hairpin probe. Anal Bioanal Chem. 2016 May;408(14):3801-9.\|[2]Rudin A, et al. Antibacterial activity of gentamicin sulfate in tissue culture. Appl Microbiol. 1970 Dec;20(6):989-90.\|[3]Kumar CG, et al. Microbial biosynthesis and applications of gentamicin: a critical appraisal.\|[4]Espersen F, et al. Effect of treatment with methicillin and gentamicin in a new experimental mouse model of foreignbody infection. Antimicrob Agents Chemother. 1994 Sep;38(9):2047-53. ACS Appl Mater Interfaces. 2019 Oct 16;11(41):38190-38204. \|ACS Infect Dis. 2024 Apr 12;10(4):1327-1338.\|Am J Physiol Cell Physiol. 2019 Aug 1;317(2):C277-C286.\|Appl Microbiol Biotechnol. 2022 Apr;106(7):2689-2702.\|Aquaculture. 2021, 736248.\|Cell Death Dis. 2023 Jan 11;14(1):15.\|Cell Host Microbe. 2024 Jul 23:S1931-3128(24)00254-3.\|Cell Transplant. Jan-Dec 2021;30:963689721997151.\|Evid Based Complement Alternat Med. 2015;2015:639412.\|Immun Inflamm Dis. 2024 Jul;12(7):e1149.\|Int J Biol Sci. 2024 Oct 7;20(14):5415-5435.\|J Ethnopharmacol. 2020 Sep 15;259:112882. \|Mol Immunol. 2017 Dec;92:151-160.\|Mol Med Rep. 2016 Dec;14(6):5304-5310.\|Mutat Res Genet Toxicol Environ Mutagen. 2023 Apr 5,503636.\|Nat Commun. 2022 Mar 2;13(1):1116.\|Research Square Print. October 6th, 2022.\|Toxicology. 2022 Nov 29;483:153386.\|AMB Express. 2024 Dec 24;14(1):141.\|Biomed Pharmacother. 2023 Nov 8:115856.\|bioRxiv. 2024 May 10.\|Cell. 2024 Feb 15;187(4):882-896.e17\|Chin J Traumatol. 2024 Jul 3:S1008-1275(24)00075-0.\|Curr Microbiol. 2023 May 31;80(7):230.\|Emerg Microbes Infect. 2024 Dec;13(1):2321981.\|Food Chem. 2022 Sep 26;403:134399.\|Int J Biol Macromol. 2025 Feb 19:141278.\|Int J Med Microbiol. 2023 Mar 28;313(2):151578.\|MedComm (2020). 2025 Jan 8;6(1):e70046.\|Microorganisms. 2024 Mar 13, 12(3), 575.\|Nat Microbiol. 2023 Mar;8(3):410-423.\|Naunyn Schmiedebergs Arch Pharmacol. 2024 Oct 1.\|Patent. US20240319170A1\|Pathogens. 2024 Nov 15;13(11):1003.\|Vet Microbiol. 2024 May, 292, 110046.\|Vet Res Commun. 2024 Sep 26.\|Virulence. 2024 Oct 10:2415952.
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ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	1405-41-0
Shipping Condition	Room temperature
Available
Manufacturer - Type	Natural Products
Manufacturer - Applications	COVID-19-anti-virus
Manufacturer - Targets	Antibiotic; Bacterial
Shipping Temperature	Room Temperature
Storage Conditions	4°C (Powder, sealed storage, away from moisture)
Molecular Weight	561.65 (Average)
Product Description	Gentamicin sulfate, an orally active aminoglycoside antibiotic, inhibits the growth of both gram-positive and gram-negative bacteria and to inhibit several strains of mycoplasma in tissue culture. Gentamicin sulfate inhibits DNase I with an IC50 of 0.57 mM[1][2][3][4].
Manufacturer - Research Area	Infection; Cancer
Solubility	DMSO: < 1 mg/mL (ultrasonic; warming; heat to 60°C)\|H2O: ≥ 30 mg/mL
Manufacturer - Pathway	Anti-infection
Isoform	Aminoglycoside
Clinical information	Launched

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