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Docetaxel (Trihydrate)

Docetaxel (Trihydrate)

Manufacturer	MedChem Express
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Amount	100 mg
Item no.	HY-B0011A-100mg
Targets	Microtubule/Tubulin; Apoptosis
CASRN	148408-66-6
eClass 6.1	30220300
eClass 9.0	32160605
Available
Product Description	Docetaxel Trihydrate (RP-56976 Trihydrate) is an antineoplastic agent and inhibits microtubule depolymerization with an IC50 value of 0.2 μM[1]. Docetaxel Trihydrate is a semisynthetic analog of taxol and attenuates the effects of bcl-2 and bcl-xL gene expression. Docetaxel Trihydrate arrests the cell cycle at G2/M and leads to cell apoptosis[1][3].
StorageTemperature	-20°C, 3 years; 4°C, 2 years (Powder)
Shipping	Room Temperature
Manufacturers Applications	Cancer-programmed cell death
MolecularWeight	861.93
Clinical_Information	Launched
Manufacturers Research_Area	Cancer
Solubility	DMSO : 250 mg/mL (ultrasonic)\|Ethanol : 50 mg/mL (ultrasonic)
Manufacturers Target	Apoptosis; Microtubule/Tubulin
Pathway	Apoptosis; Cell Cycle/DNA Damage; Cytoskeleton
Manufacturers Product type	Reference compound

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HY-B0011A-100mg-safety-datasheet.pdf