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Quetiapine (hemifumarate)

Quetiapine (hemifumarate)

Manufacturer	MedChem Express
Category	Food Safety Histamines Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Clone	N/A
Amount	10mM/1mL
Item no.	HY-B0031-10mM
Targets	5-HT Receptor; Dopamine Receptor
CASRN	111974-72-2
eClass 6.1	30220300
eClass 9.0	32160605
Available
Product Description	Quetiapine hemifumarate is a 5-HT receptors agonist with a pEC50 of 4.77 for human 5-HT1A receptor. Quetiapine hemifumarate is a dopamine receptor antagonist with a pIC50 of 6.33 for human D2 receptor. Quetiapine hemifumarate has moderate to high affinity for the human D2, HT1A, 5-HT2A, 5-HT2C receptor with pKis of 7.25, 5.74, 7.54, 5.55. Antidepressant and anxiolytic effects[1].
StorageTemperature	4°C (Powder, sealed storage, away from moisture)
Shipping	Room Temperature
Manufacturers Applications	Neuroscience-Neuromodulation
MolecularWeight	441.54
Clinical_Information	Launched
Manufacturers Research_Area	Neurological Disease
Solubility	DMSO : 50 mg/mL (ultrasonic)\|H2O : 1.25 mg/mL (ultrasonic)
Manufacturers Target	5-HT Receptor; Dopamine Receptor
Isoform	5-HT1 Receptor; 5-HT2 Receptor
Pathway	GPCR/G Protein; Neuronal Signaling
Manufacturers Product type	Reference compound

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HY-B0031-10mM-safety-datasheet.pdf