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Tigecycline (hydrochloride)

Tigecycline (hydrochloride)

Item no.	HY-B0117A-200mg
Manufacturer	MedChem Express
CASRN	197654-04-9
Amount	200 mg
Quantity options	100 mg 10 mg 1 ea 200 mg 500 mg 50 mg
Category	Oncology Neuroscience Neural Lineage Markers By Cell Type Blastoma Carcinoma Cell Biology Cell Status Proliferation Inhibitors & Compound Libraries Small Molecules By Organ Bladder Cancer
Type	Inhibitors
Specific against	other
Citations	Ann Lab Med. 2021 May 1;41(3):293-301. Emerg Microbes Infect. 2024 Dec;13(1):2321981. Adv Ther (Weinh). 2024 Jan 12. Animal Diseases. 02 November 2021. Ann Clin Microbiol Antimicrob. 2024 Aug 20;23(1):73. Antimicrob Agents Chemother. 2019 May 24;63(6). pii: e00470-19. Antimicrob Agents Chemother. 2023 Jan 23;e0145922. Antimicrob Agents Chemother. 2024 Jan 30:e0112023. Antimicrob Agents Chemother. 2024 Oct 29:e0094524. Biomed Pharmacother. 2023 Nov 8:115856. Clin Exp Pharmacol Physiol. 2023 Apr 22. Cureus. 2024 Dec 1;16(12):e74917. EBioMedicine. 2022 Apr;78:103943. Infect Drug Resist. 2020 Jul 28;13:2617-2629. Infect Drug Resist. 2021 Jun 30;14:2499-2507. Infect Drug Resist. 2023 Apr 17. Int J Antimicrob Agents. 2018 Aug;52(2):269-271. J Antibiot (Tokyo). 2022 Jun 27. Microb Pathog. 2020 Dec;149:104502. Microbiol Spectr. 2022 Dec 8;e0323822. Microbiol Spectr. 2023 May 4;e0071823. Microorganisms. 2024 Mar 13, 12(3), 575. Nat Commun. 2022 Mar 2;13(1):1116. Nat Commun. 2024 Jun 28;15(1):5481. SLAS Discov. 2020 Sep;25(8):895-905. Vet Microbiol. 2024 May, 292, 110046. World J Microbiol Biotechnol. 2024 Jun 6;40(8):233. [1]Jitkova Y, et al. A novel formulation of tigecycline has enhanced stability and sustained antibacterial and antileukemic activity. PLoS One. 2014 May 28;9(5):e95281. [2]Falagas ME, et al. Activity of TP-6076 against carbapenem-resistant Acinetobacter baumannii isolates collected from inpatients in Greek hospitals. Int J Antimicrob Agents. 2018 Aug;52(2):269-271.
Smiles	O=C(C(C1=O)=C(O)[C@@H](N(C)C)[C@]2([H])C[C@]3([H])CC4=C(C(C3=C(O)[C@@]21O)=O)C(O)=C(NC(CNC(C)(C)C)=O)C=C4N(C)C)N.Cl
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	GAR-936 hydrochloride
Shipping Condition	Room temperature
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	Cancer-programmed cell death
Manufacturer - Targets	Antibiotic; Autophagy; Bacterial
Shipping Temperature	Room temperature
Molecular Weight	622.11
Product Description	Tigecycline hydrochloride (GAR-936 hydrochloride) is a broad-spectrum glycylcycline antibiotic. The mean inhibitory concentration (MIC) of Tigecycline for E. coli (MG1655 strain) is approximately 125 ng/mL[1]. MIC50 and MIC90 are 1 and 2 mg/L for Acinetobacter baumannii (A. baumannii), respectively[2].
Manufacturer - Research Area	Cancer; Infection
Solubility	10 mM in DMSO
Manufacturer - Pathway	Anti-infection; Autophagy
Clinical information	Launched

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Amount: 200 mg

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