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Lidocaine (hydrochloride)

Lidocaine (hydrochloride)

Manufacturer	MedChem Express
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Clone	N/A
Amount	10 g
Item no.	HY-B0185A-10g
Targets	Sodium Channel; MEK; ERK; NF-κB; Apoptosis
CASRN	73-78-9
eClass 6.1	30220300
eClass 9.0	32160605
Available
Product Description	Lidocaine hydrochloride (Lignocaine hydrochloride) inhibits sodium channels involving complex voltage and using dependence[1]. Lidocaine hydrochloride decreases growth, migration and invasion of gastric carcinoma cells via up-regulating miR-145 expression and further inactivation of MEK/ERK and NF-κB signaling pathways. Lidocaine hydrochloride is an amide derivative and a agent to treat ventricular arrhythmia and an effective tumor-inhibitor[2].
StorageTemperature	4°C (Powder, sealed storage, away from moisture and light)
Shipping	Room Temperature
Manufacturers Applications	Cancer-Kinase/protease
MolecularWeight	270.80
Clinical_Information	Launched
Manufacturers Research_Area	Cancer; Cardiovascular Disease
Solubility	DMSO : ≥ 100 mg/mL\|H2O : ≥ 100 mg/mL
Manufacturers Target	Apoptosis; ERK; MEK; NF-κB; Sodium Channel
Isoform	ERK; MEK; NF-κB
Pathway	Apoptosis; MAPK/ERK Pathway; Membrane Transporter/Ion Channel; NF-κB; Stem Cell/Wnt
Manufacturers Product type	Reference compound

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HY-B0185A-10g-safety-datasheet.pdf