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Acetylcysteine

Acetylcysteine

Item no.	HY-B0215-10mM
Manufacturer	MedChem Express
CASRN	616-91-1
Amount	10 mM/1 mL
Quantity options	10 g 10 mM/1 mL 500 mg 5 g
Category	Oncology Neuroscience Molecular Targets for Neuroscience Targets for Rodent Neurosciences Neural Signaling Inhibitors & Compound Libraries Small Molecules By Organ Lung Cancer Skin Cancer
Type	Inhibitors
Specific against	other
Purity	99.86
Citations	[1]Halasi M, et al. ROS inhibitor N-acetyl-L-cysteine antagonizes the activity of proteasome inhibitors. Biochem J. 2013 Sep 1;454(2):201-8.\|[2]Ferrari G, et al. N-acetylcysteine (D- and L-stereoisomers) prevents apoptotic death of neuronal cells. J Neurosci. 1995 Apr;15(4):2857-66.\|[3]Tsai JC, et al. Induction of apoptosis by pyrrolidinedithiocarbamate and N-acetylcysteine in vascular smooth muscle cells. J Biol Chem. 1996 Feb 16;271(7):3667-70.\|[4]Yan CY, et al. Prevention of PC12 cell death by N-acetylcysteine requires activation of the Ras pathway. J Neurosci. 1998 Jun 1;18(11):4042-9.\|[5]Farr SA, et al. The antioxidants alpha-lipoic acid and N-acetylcysteine reverse memory impairment and brain oxidative stress in aged SAMP8 mice. J Neurochem. 2003 Mar;84(5):1173-83.\|[6]Kalimeris K, et al. N-acetylcysteine ameliorates liver injury in a rat model of intestinal ischemia reperfusion. J Surg Res. 2016 Dec;206(2):263-272.\|[7]Garigliany MM, et al. N-acetylcysteine lacks universal inhibitory activity against influenza A viruses. J Negat Results Biomed. 2011 May 9;10:5.\|[8]Gu Q, et al. Disulfidptosis, a novel cell death pathway: molecular landscape and therapeutic implications[J]. Aging Dis, 2024, 10.
Smiles	SC[C@@H](C(O)=O)NC(C)=O
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	N-Acetylcysteine,N-Acetyl-L-cysteine,NAC
Shipping Condition	Room temperature
Available
Manufacturer - Type	Natural Products
Manufacturer - Applications	Neuroscience-Neurodegeneration
Manufacturer - Targets	Apoptosis; Disulfidptosis; Endogenous Metabolite; Ferroptosis; Influenza Virus; Reactive Oxygen Species (ROS)
Shipping Temperature	Room Temperature
Storage Conditions	4°C (Powder, protect from light)
Molecular Weight	163.20
Product Description	Acetylcysteine (N-Acetylcysteine) is a mucolytic agent which reduces the thickness of the mucus. Acetylcysteine is a ROS inhibitor. Acetylcysteine is a cysteine precursor, prevents hemin-induced ferroptosis by neutralizing toxic lipids generated by arachidonate-dependent activity of 5-lipoxygenases. Acetylcysteine induces cell apoptosis. Acetylcysteine also has anti-influenza virus activities. In addition, Acetylcysteine is the most stable form of cysteine during drug delivery and can be used in disulfidptosis studies[1][2][3][4][5][6][7][8].
Manufacturer - Research Area	Infection; Neurological Disease; Cancer
Solubility	DMSO: 100 mg/mL (ultrasonic)\|H2O: 100 mg/mL (ultrasonic)
Manufacturer - Pathway	Anti-infection; Apoptosis; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Isoform	Human Endogenous Metabolite
Clinical information	Launched

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HY-B0215-10mM-safety-datasheet.pdf