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Methyldopa

Methyldopa

Item no.	HY-B0225-1g
Manufacturer	MedChem Express
CASRN	555-30-6
Amount	1 g
Quantity options	100 mg 10 mM/1 mL 1 ea 1 g 500 mg 50 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	98.25
Citations	[1]Sweet CS. New centrally acting antihypertensive drugs related to methyldopa and clonidine. Hypertension. 1984;6(5 Pt 2):II51-II56.\|[2]Fox GR, et al. The effects of phenobarbital, atropine, L-alpha-methyldopa, and DL-propranolol on dieldrin-induced hyperglycemia in the adult rat. Toxicol Appl Pharmacol. 1985;78(3):342-350. Clin Chem. 2019 Dec;65(12):1522-1531. \|Cell Rep Methods. 2023 Oct 23;3(10):100599.
Smiles	OC1=C(O)C=CC(C[C@@](C)(C(O)=O)N)=C1
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	L-(-)-α-Methyldopa,MK-351
Shipping Condition	Room temperature
Available
Manufacturer - Type	Natural Products
Manufacturer - Applications	Metabolism-protein/nucleotide metabolism
Manufacturer - Targets	Adrenergic Receptor; Endogenous Metabolite
Shipping Temperature	Room Temperature
Storage Conditions	-20°C, 3 years; 4°C, 2 years (Powder)
Molecular Weight	211.22
Product Description	Methyldopa (L-(-)-α-Methyldopa), a potent antihyoertensive agent, is an alpha-adrenergic agonist (selective for α2-adrenergic receptors). Methyldopa is a proagent and is metabolized (α-Methylepinephrine) in the central nervous system[1][2].
Manufacturer - Research Area	Cardiovascular Disease; Endocrinology
Solubility	DMSO: 50 mg/mL (ultrasonic; warming; heat to 60°C)
Manufacturer - Pathway	GPCR/G Protein; Metabolic Enzyme/Protease; Neuronal Signaling
Isoform	α adrenergic receptor
Clinical information	Launched

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HY-B0225-1g-safety-datasheet.pdf