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Chlorprothixene

Chlorprothixene

Item no.	HY-B0274-10mM
Manufacturer	MedChem Express
CASRN	113-59-7
Amount	10mM/1mL
Quantity options	100 mg 10mM/1mL 200 mg 500 mg 50 mg
Category	Food Safety Histamines Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Clone	N/A
Specific against	other
Purity	99.87
Formula	C18H18ClNS
Citations	[1]Y von Coburg, et al. Potential utility of histamine H3 receptor antagonist pharmacophore in antipsychotics. Bioorg Med Chem Lett. 2009 Jan 15;19(2):538-42. [2]B L Roth, et al. Binding of typical and atypical antipsychotic agents to 5-hydroxytryptamine-6 and 5-hydroxytryptamine-7 receptors. J Pharmacol Exp Ther. 1994 Mar;268(3):1403-10.
Smiles	CN(C)CC/C=C1C2=C(SC3=C\1C=CC=C3)C=CC(Cl)=C2
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	113-59-7
Shipping Condition	Room temperature
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	Neuroscience-Neuromodulation
Manufacturer - Targets	Bacterial; Dopamine Receptor; Histamine Receptor
Shipping Temperature	Room Temperature
Storage Conditions	-20°C, 3 years; 4°C, 2 years (Powder)
Molecular Weight	315.86
Product Description	Chlorprothixene is a dopamine and histamine receptors antagonist with Kis of 18 nM, 2.96 nM, 4.56 nM, 9 nM and 3.75 nM for hD1, hD2, hD3, hD5 and hH1 receptors, respectively. Antipsychotic activity[1].
Manufacturer - Research Area	Neurological Disease
Solubility	DMSO : 12.5 mg/mL (ultrasonic)\|H2O : < 0.1 mg/mL
Manufacturer - Pathway	Anti-infection; GPCR/G Protein; Immunology/Inflammation; Neuronal Signaling
Isoform	D1 Receptor; D2 Receptor; D3 Receptor; D5 Receptor; H1 Receptor
Clinical information	Launched

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HY-B0274-10mM-safety-datasheet.pdf