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Levofloxacin

Levofloxacin

Item no.	HY-B0330-100mg
Manufacturer	MedChem Express
CASRN	100986-85-4
Amount	100 mg
Quantity options	100 mg 10 mM/1 mL 5 g
Category	Food Safety Antibiotics Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	99.93
Citations	[1]Drlica K, et al. DNA gyrase, topoisomerase IV, and the 4-quinolones. Microbiol Mol Biol Rev. 1997 Sep;61(3):377-92. \|[2]Smee DF, et al. A review of compounds exhibiting anti-orthopoxvirus activity in animal models. Antiviral Res. 2003 Jan;57(1-2):41-52.\|[3]Rand A, et al. Effect of levofloxacin on some body tissues in mice. Effect of levofloxacin on some body tissues in mice. Iraqi Journal of Veterinary Sciences, 2021.\|[4]JI B, et al. In vitro and in vivo activities of levofloxacin against Mycobacterium tuberculosis. Antimicrob Agents Chemother. 1995 Jun;39(6):1341-4. ACS Infect Dis. 2024 Apr 12;10(4):1327-1338.\|AMB Express. 2024 Dec 24;14(1):141.\|Antibiotics (Basel). 2022, 11(2), 192.\|Antimicrob Agents Chemother. 2021 Feb 17;65(3):e01921-20.\|bioRxiv. 2024 May 10.\|bioRxiv. 2025 January 19.\|Cell Rep Methods. 2023 Oct 23;3(10):100599.\|Chin J Traumatol. 2024 Jul 3:S1008-1275(24)00075-0.\|Clin Chem. 2019 Dec;65(12):1522-1531. \|PLoS One. 2024 Apr 18;19(4):e0298577.\|Results Chem. 2024 Oct.\|Toxics. 2025 Feb 5.\|Emerg Microbes Infect. 2024 Dec;13(1):2321981.\|Nat Commun. 2022 Mar 2;13(1):1116.
Smiles	O=C(C(C1=O)=CN2[C@@H](C)COC3=C(N4CCN(C)CC4)C(F)=CC1=C23)O
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	(-)-Ofloxacin
Shipping Condition	Room temperature
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	COVID-19-anti-virus
Manufacturer - Targets	Antibiotic; Bacterial; DNA/RNA Synthesis; Orthopoxvirus; Topoisomerase
Shipping Temperature	Room Temperature
Storage Conditions	4°C (Powder, protect from light)
Molecular Weight	361.37
Product Description	Levofloxacin ((-)-Ofloxacin) is an orally active antibiotic and is active against both Gram-positive and Gram-negative bacteria. Levofloxacin inhibits the DNA gyrase and topoisomerase IV. Levofloxacin can be used for chronic periodontitis, airway inflammation and BK Viremia research. Levofloxacin shows anti-orthopoxvirus activity[1][2][3][4][5].
Manufacturer - Research Area	Infection; Cancer
Solubility	DMSO: 10 mg/mL (ultrasonic)\|H2O: ≥ 5 mg/mL
Manufacturer - Pathway	Anti-infection; Cell Cycle/DNA Damage
Isoform	Quinolone; Topoisomerase
Clinical information	Launched

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HY-B0330-100mg-safety-datasheet.pdf