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Propylthiouracil

Propylthiouracil

Item no.	HY-B0346-10mM
Manufacturer	MedChem Express
CASRN	51-52-5
Amount	10 mM/1 mL
Quantity options	100 mg 10 mM/1 mL 500 mg
Category	Oncology Inhibitors & Compound Libraries Small Molecules By Organ Thyroid Cancer
Type	Inhibitors
Specific against	other
Purity	99.88
Citations	[1]Lamis Chamas, et al. A Fine Regulation of the Hippocampal Thyroid Signalling Protects Hypothyroid Mice against Glial Cell Activation. Int J Mol Sci. 2022 Oct 8;23(19):11938.\|[2]Utsana Puapermpoonsiri, et al. Synergistic effect of phospholipid-based liposomes and propylthiouracil on U-937 cell growth. J Liposome Res. 2005;15(3-4):215-27.
Smiles	O=C(C=C(CCC)N1)NC1=S
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	6-n-Propylthiouracil,6-Propyl-2-thiouracil,PTU
Shipping Condition	Room temperature
Available
Manufacturer - Type	Reference compound
Manufacturer - Targets	Thyroid Hormone Receptor
Shipping Temperature	Room Temperature
Storage Conditions	-20°C, 3 years; 4°C, 2 years (Powder)
Molecular Weight	170.23
Product Description	Propylthiouracil (6-n-Propylthiouracil), a thioamide antithyroid agent, is an orally active thyroperoxidase and type-1 deiodinase (DIO1) inhibitor. Propylthiouracil can be used for the Graves disease and hyperthyroidism research[1].
Manufacturer - Research Area	Endocrinology
Solubility	DMSO: ≥ 100 mg/mL\|H2O: < 0.1 mg/mL (ultrasonic)
Manufacturer - Pathway	Vitamin D Related/Nuclear Receptor
Clinical information	Launched

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HY-B0346-10mM-safety-datasheet.pdf