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Fenticonazole (Nitrate)

Fenticonazole (Nitrate)

Item no.	HY-B0359-50mg
Manufacturer	MedChem Express
CASRN	73151-29-8
Amount	50 mg
Quantity options	100 mg 10 mM/1 mL 10 mg 25 mg 50 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	98.92
Citations	[1]Fernandez-Alba, J., et al., Fenticonazole nitrate for treatment of vulvovaginitis: efficacy, safety, and tolerability of 1-gram ovules, administered as ultra-short 2-day regimen. J Chemother, 2004. 16(2): p. 179-86.\|[2]Rofida Albash, et al. Ultra-deformable liposomes containing terpenes (terpesomes) loaded fenticonazole nitrate for treatment of vaginal candidiasis: Box-Behnken design optimization, comparative ex vivo and in vivo studies. Drug Deliv. 2020 Dec;27(1):1514-1523. Pharmacol Res. 2021 Aug 27;105860.\|Bioorg Chem. 7 October 2022, 106191.\|BMC Cancer. 2024 Mar 25;24(1):371.\|Molecules. 2024 Oct 15;29(20):4881.
Smiles	[O-][N+](O)=O.ClC1=CC=C(C(OCC2=CC=C(SC3=CC=CC=C3)C=C2)CN4C=CN=C4)C(Cl)=C1
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	REC 15-1476
Shipping Condition	Room temperature
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	COVID-19-immunoregulation
Manufacturer - Targets	Antibiotic; Fungal
Shipping Temperature	Room Temperature
Storage Conditions	4°C (Powder, sealed storage, away from moisture)
Molecular Weight	518.41
Product Description	Fenticonazole Nitrate is an antifungal imidazole ring derivative. Fenticonazole Nitrate operates via hindering ergosterol integration, and sequentially destructing the cytoplasmatic outer membrane. Fenticonazole Nitrate is effective against Gram-positive bacteria, mycoses, and vaginal candidiasis[1][2].
Manufacturer - Research Area	Infection
Solubility	DMSO: ≥ 100 mg/mL
Manufacturer - Pathway	Anti-infection
Clinical information	Launched

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HY-B0359-50mg-safety-datasheet.pdf