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Methacycline (hydrochloride)

Methacycline (hydrochloride)

Item no.	HY-B0449-200mg
Manufacturer	MedChem Express
CASRN	3963-95-9
Amount	200 mg
Quantity options	100 mg 10 mM/1 mL 200 mg 500 mg
Category	Oncology Food Safety Antibiotics Neuroscience Neural Lineage Markers By Cell Type Blastoma Carcinoma Cell Biology Cell Status Proliferation Inhibitors & Compound Libraries Small Molecules By Organ Bladder Cancer
Type	Inhibitors
Specific against	other
Purity	99.71
Citations	[1]Ying Xi, et al. Inhibition of epithelial-to-mesenchymal transition and pulmonary fibrosis by methacycline. Am J Respir Cell Mol Biol. 2014 Jan;50(1):51-60.
Smiles	O[C@@](C(O)=C(C(C1=C2C=CC=C1O)=O)[C@](C2=C)([H])[C@@H]3O)(C(C(C(N)=O)=C4O)=O)[C@]3([H])[C@@H]4N(C)C.Cl
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	3963-95-9
Shipping Condition	Room temperature
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	COVID-19-immunoregulation
Manufacturer - Targets	Antibiotic; Bacterial
Shipping Temperature	Room Temperature
Storage Conditions	4°C (Powder, sealed storage, away from moisture)
Molecular Weight	478.88
Product Description	Methacycline hydrochloride is a tetracycline antibiotic and can inhibits bacterial protein synthesis. Methacycline hydrochloride is a potent epithelial-mesenchymal transition (EMT) inhibitor. Methacycline hydrochloride blocks EMT in vitro and fibrogenesis in vivo without directly affecting TGF-β1 Smad signaling. Methacycline hydrochloride is an antimicrobial and has the potential for pulmonary fibrosis[1].
Manufacturer - Research Area	Infection
Solubility	DMSO: 50 mg/mL (ultrasonic)\|H2O: 6.67 mg/mL (ultrasonic)
Manufacturer - Pathway	Anti-infection
Isoform	Tetracycline
Clinical information	Launched

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HY-B0449-200mg-safety-datasheet.pdf