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Tioxolone

Tioxolone

Item no.	HY-B0483-10mM
Manufacturer	MedChem Express
CASRN	4991-65-5
Amount	10 mM/1 mL
Quantity options	10 mM/1 mL 1 g 500 mg
Category	Food Safety Antibiotics Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	98.83
Citations	[1]Maryam Hakimi Parizi, et al. Tioxolone niosomes exert antileishmanial effects on Leishmania tropica by promoting promastigote apoptosis and immunomodulation. Asian Pacific Journal of Tropical Medicine 2019; 12(8): 365-374.\|[2]Parizi M H, et al. Tioxolone niosomes exert antileishmanial effects on Leishmania tropica by promoting promastigote apoptosis and immunomodulation[J]. Asian Pacific Journal of Tropical Medicine, 2019, 12(8): 365-374.\|[3]Prajapat S K, et al. Avobenzone, Guaiazulene and Tioxolone identified as potent autophagy inducers in a high-throughput image based screen for autophagy flux[J]. Autophagy Reports, 2022, 1(1): 523-536.
Smiles	O=C1OC2=CC(O)=CC=C2S1
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	4991-65-5
Shipping Condition	Room temperature
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	Metabolism-sugar/lipid metabolism
Manufacturer - Targets	Apoptosis; Autophagy; Carbonic Anhydrase; Parasite
Shipping Temperature	Room Temperature
Storage Conditions	-20°C, 3 years; 4°C, 2 years (Powder)
Molecular Weight	168.17
Product Description	Tioxolone is an inhibitor for the carbonic anhydrase. Tioxolone exhibits anti-leishmanial, antitumor, and anti-inflammatory activities. Tioxolone can be used in research of acne and psoriasis[1][2][3].
Manufacturer - Research Area	Cancer; Infection; Inflammation/Immunology
Solubility	DMSO: ≥ 100 mg/mL\|H2O: 0.67 mg/mL (ultrasonic)
Manufacturer - Pathway	Anti-infection; Apoptosis; Autophagy; Metabolic Enzyme/Protease
Clinical information	Launched

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HY-B0483-10mM-safety-datasheet.pdf