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Clorsulon

Clorsulon

Item no.	HY-B0488-100mg
Manufacturer	MedChem Express
CASRN	60200-06-8
Amount	100 mg
Quantity options	100 mg 10 mM/1 mL 25 mg 500 mg 50 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	99.99
Citations	[1]Mrozik, H., et al., 4-amino-6-(trichloroethenyl)-1,3-benzenedisulfonamide, a new, potent fasciolicide. J Med Chem, 1977. 20(9): p. 1225-7.\|[2]Meaney, M., et al., Transmission electron microscope study of the ultrastructural changes induced in the tegument and gut of Fasciola hepatica following in vivo drug treatment with clorsulon. Parasitol Res, 2004. 92(3): p. 232-41.
Smiles	O=S(C1=C(/C(Cl)=C(Cl)\Cl)C=C(N)C(S(=O)(N)=O)=C1)(N)=O
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	L631529,MK401
Shipping Condition	Room temperature
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	COVID-19-immunoregulation
Manufacturer - Targets	Parasite
Shipping Temperature	Room Temperature
Storage Conditions	-20°C, 3 years; 4°C, 2 years (Powder)
Molecular Weight	380.66
Product Description	Clorsulon (L631529; MK401) is an orally active flukicidal agent against liver flukes (Fasciola hepatica and Fasciola gigantica) infections in calves and sheep. Clorsulon is also a competitive inhibitor of both 3-phosphoglycorate and ATP andinhibits glucose utilization and acetate and propionate formation by mature Fasciola hepatica in vitro[1][2].
Manufacturer - Research Area	Infection
Solubility	DMSO: 100 mg/mL (ultrasonic)
Manufacturer - Pathway	Anti-infection
Isoform	Schistosome
Clinical information	No Development Reported

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HY-B0488-100mg-safety-datasheet.pdf