Comparison

Sulfathiazole (sodium) European Partner

Item no. HY-B0507A-10g
Manufacturer MedChem Express
CASRN 144-74-1
Amount 10 g
Quantity options 10 g 10 mM/1 mL 1 g 500 mg
Category
Type Inhibitors
Specific against other
Purity 99.92
Citations [1]Ji K, Choi K, Lee S, Park S, Khim JS, Jo EH, Choi K, Zhang X, Giesy JP. Effects of sulfathiazole, oxytetracycline and chlortetracycline on steroidogenesis in the human adrenocarcinoma (H295R) cell line and freshwater fish Oryzias latipes. J Hazard Mater. 2010 Oct 15;182(1-3):494-502.|[2]Endicott, et al. Lesions in rats given sulfathiazole, sulfadiazine, sulfanilamide, sulfamerazine, sulfapyrazine, or acetylsulfadiazine in purified diets. Public Health Reports (1896-1970) (1944): 49-54.|[3]Zor, et al. Sulfathiazole as potential corrosion inhibitor for copper in 0.1 M NaCl. Protection of Metals and Physical Chemistry of Surfaces 50 (2014): 530-537.
Research Square Preprint. 2021 Aug.|Chemosphere. 2019 Jun;225:378-387. |Theranostics. 2022 Jan 1;12(3):1187-1203.
Smiles O=S(C1=CC=C(N)C=C1)([N-]C2=NC=CS2)=O.[Na+]
ECLASS 10.1 32160490
ECLASS 11.0 32160490
UNSPSC 12000000
Alias Soluthiazomide
Shipping Condition Room temperature
Available
Manufacturer - Type
Reference compound
Manufacturer - Applications
COVID-19-immunoregulation
Manufacturer - Targets
Antibiotic; Bacterial
Shipping Temperature
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Molecular Weight
277.30
Product Description
Sulfathiazole sodium is an orally active, endocrine disruptor targeting the steroidogenic pathway, specifically enhancing the activity of CYP19 in human adrenal cancer cells (H295R) and upregulating the mRN expression of CYP17, CYP19, and 3β-HSD. Sulfathiazole sodium increases the production of 17-estradiol (E2) and has endocrine disrupting effects on aquatic organisms such as the Japanese medaka fish. Sulfathiazole sodium is also a cathodic corrosion inhibitor. It inhibits the corrosion of copper by chloride ions through chemical and physical adsorption on the copper surface, reduces the corrosion current density and shifts the corrosion potential negatively[1][2][3].
Manufacturer - Research Area
Cancer; Endocrinology
Solubility
DMSO: 140 mg/mL (ultrasonic)|H2O: 140 mg/mL (ultrasonic)
Manufacturer - Pathway
Anti-infection
Clinical information
Launched

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 10 g
Available: In stock
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