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Hydroxyzine (dihydrochloride)

Hydroxyzine (dihydrochloride)

Item no.	HY-B0548A-500mg
Manufacturer	MedChem Express
CASRN	2192-20-3
Amount	500 mg
Quantity options	100 mg 10mM/1mL 500 mg
Category	Oncology Food Safety Histamines Inhibitors & Compound Libraries Small Molecules By Organ Bladder Cancer Testicular & Prostate Cancer
Type	Inhibitors
Clone	N/A
Specific against	other
Purity	99.81
Formula	C21H29Cl3N2O2
Citations	[1]Minogiannis, P., et al., Hydroxyzine inhibits neurogenic bladder mast cell activation. Int J Immunopharmacol, 1998. 20(10): p. 553-63. [2]Morichi, R. and G. Pepeu, A study of the influence of hydroxyzine and diazepam on morphine antinociceptoion in the rat. Pain, 1979. 7(2): p. 173-80. [3]Nikita Shekhar Sawantdesai, et al. Evaluation of anxiolytic effects of aripiprazole and hydroxyzine as a combination in mice. J Basic Clin Pharm. 2016 Sep;7(4):97-104.
Smiles	ClC1=CC=C(C=C1)C(C2=CC=CC=C2)N3CCN(CCOCCO)CC3.Cl.Cl
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	2192-20-3
Shipping Condition	Room temperature
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	COVID-19-immunoregulation
Manufacturer - Targets	Histamine Receptor
Shipping Temperature	Room Temperature
Storage Conditions	4°C (Powder, sealed storage, away from moisture and light)
Molecular Weight	447.83
Product Description	Hydroxyzine dihydrochloride, a benzodiazepine antihistamine agent, acts as a orally active histamine?H1-receptor and serotonin antagonist. Hydroxyzine dihydrochloride has anxiolytic effect and can be used forthe research of generalised anxiety disorder[1][2].
Manufacturer - Research Area	Inflammation/Immunology; Endocrinology
Solubility	H2O : ≥ 150 mg/mL
Manufacturer - Pathway	GPCR/G Protein; Immunology/Inflammation; Neuronal Signaling
Isoform	H1 Receptor
Clinical information	Launched

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HY-B0548A-500mg-safety-datasheet.pdf