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Flavoxate (hydrochloride)

Flavoxate (hydrochloride)

Item no.	HY-B0549A-10mM
Manufacturer	MedChem Express
CASRN	3717-88-2
Amount	10 mM/1 mL
Quantity options	100 mg 10 mM/1 mL 1 g 500 mg 5 g
Category	Oncology Inhibitors & Compound Libraries Small Molecules By Organ Bladder Cancer Testicular & Prostate Cancer Brain Cancer
Type	Inhibitors
Specific against	other
Purity	99.70
Citations	[1]Dansette, P.M., et al. HMG-CoA reductase activity in human liver microsomes: comparative inhibition by statins. Exp Toxicol Pathol, 2000. 52(2): p. 145-8.\|[2]Kimura, Y., et al., Mechanisms of the suppression of the bladder activity by flavoxate. Int J Urol, 1996. 3(3): p. 218-27.\|[3]Oka, M., et al., Brain pertussis toxin-sensitive G proteins are involved in the flavoxate hydrochloride-induced suppression of the micturition reflex in rats. Brain Res, 1996. 727(1-2): p. 91-8.
Smiles	O=C(C1=C2C(C(C(C)=C(C3=CC=CC=C3)O2)=O)=CC=C1)OCCN4CCCCC4.Cl
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	Rec-7-0040,DW61
Shipping Condition	Room temperature
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	Neuroscience-Neuromodulation
Manufacturer - Targets	Calcium Channel; mAChR; Phosphodiesterase (PDE)
Shipping Temperature	Room Temperature
Storage Conditions	4°C (Powder, sealed storage, away from moisture)
Molecular Weight	427.92
Product Description	Flavoxate hydrochloride is a potent and competitive phosphodiesterase (PDE) inhibitor. Flavoxate hydrochloride is an antispasmodic agent and muscarinic mAChR antagonist. Flavoxate hydrochloride shows moderate calcium antagonistic activity and local anesthetic effect. Flavoxate hydrochloride can be used for the research of overactive bladder (OAB) and lower urinary tract infections[1].
Manufacturer - Research Area	Neurological Disease
Solubility	DMSO: 3.33 mg/mL (ultrasonic)\|H2O: 5 mg/mL (ultrasonic)
Manufacturer - Pathway	GPCR/G Protein; Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease; Neuronal Signaling
Clinical information	Launched

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HY-B0549A-10mM-safety-datasheet.pdf