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Etonogestrel

Etonogestrel

Item no.	HY-B0652-50mg
Manufacturer	MedChem Express
CASRN	54048-10-1
Amount	50 mg
Quantity options	100 mg 10 mM/1 mL 10 mg 200 mg 50 mg 5 mg
Category	Oncology Food Safety Hormones Inhibitors & Compound Libraries Small Molecules By Organ Breast Cancer
Type	Inhibitors
Specific against	other
Purity	99.14
Citations	[1]http://www.drugbank.ca/drugs/DB00294\|[2]Dionne D. Maddox, et al. Etonogestrel (Implanon), Another Treatment Option for Contraception. P T. 2008 Jun; 33(6): 337–347.\|[3]Ozlem Guzeloglu Kayisli, et al. Progestins Upregulate FKBP51 Expression in Human Endometrial Stromal Cells to Induce Functional Progesterone and Glucocorticoid Withdrawal: Implications for Contraceptive- Associated Abnormal Uterine Bleeding. PLoS One. 2015 Oct 5;10(10):e0137855.
Smiles	CC[C@]([C@]1(O)C#C)(C2)[C@](CC1)([H])[C@@](CCC3=CC4=O)([H])[C@]([C@@]3([H])CC4)([H])C2=C
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	3-Oxodesogestrel,3-keto-Desogestrel
Shipping Condition	Room temperature
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	Neuroscience-Neuromodulation
Manufacturer - Targets	Drug Metabolite; Endogenous Metabolite; Estrogen Receptor/ERR; FKBP; Progesterone Receptor
Shipping Temperature	Room Temperature
Storage Conditions	-20°C, 3 years; 4°C, 2 years (Powder)
Molecular Weight	324.46
Product Description	Etonogestrel (3-Oxodesogestrel), a biologically active metabolite of progestin Desogestrel, binds with high affinity to progesterone receptors and estrogen receptors in the target organs[1]. Etonogestrel induce FKBP51 mRNA and protein expression in cultured human endometrial stromal cells (HESCs)[2].
Manufacturer - Research Area	Endocrinology
Solubility	DMSO: 50 mg/mL (ultrasonic)
Manufacturer - Pathway	Apoptosis; Autophagy; Cell Cycle/DNA Damage; Immunology/Inflammation; Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor
Clinical information	Launched

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Amount: 50 mg

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