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Fotemustine

Fotemustine

Item no.	HY-B0733-10mg
Manufacturer	MedChem Express
CASRN	92118-27-9
Amount	10 mg
Quantity options	10 mg 5 mg
Category	Oncology Inhibitors & Compound Libraries Small Molecules By Organ Skin Cancer
Type	Inhibitors
Specific against	other
Purity	91.94
Citations	[1]Brakenhoff JP, et al. Molecular mechanisms of toxic effects of fotemustine in rat hepatocytes and subcellular rat liver fractions. Carcinogenesis. 1996 Apr;17(4):715-24.\|[2]Merlin JL, et al. Enhancement of fotemustine (Muphoran) cytotoxicity by amifostine in malignant melanoma cell lines. Anticancer Drugs. 2002 Feb;13(2):141-7.
Smiles	CC(P(OCC)(OCC)=O)NC(N(CCCl)N=O)=O
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	S10036
Shipping Condition	Room temperature
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	Cancer-programmed cell death
Manufacturer - Targets	DNA Alkylator/Crosslinker
Shipping Temperature	Room Temperature
Storage Conditions	4°C (Powder, protect from light)
Molecular Weight	315.69
Product Description	Fotemustine is a DNA-alkylating agent, with antitumor activity.
Manufacturer - Research Area	Cancer
Solubility	DMSO: ≥ 3.2 mg/mL
Manufacturer - Pathway	Cell Cycle/DNA Damage
Clinical information	Launched

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