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Benfluorex (hydrochloride)

Benfluorex (hydrochloride)

Item no.	HY-B1058-10mM
Manufacturer	MedChem Express
CASRN	23642-66-2
Amount	10 mM/1 mL
Quantity options	100 mg 10 mM/1 mL 500 mg
Category	Metabolism Diabetes Cholesterol & Lipid Metabolism Regulation of Appetite Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	99.85
Citations	[1]Lee SH, et al. Identification of alverine and benfluorex as HNF4α activators. ACS Chem Biol. 2013 Aug 16;8(8):1730-6.\|[2]Kohl C, et al. Effects of benfluorex on fatty acid and glucose metabolism in isolated rat hepatocytes: from metabolic fluxes to gene expression. Diabetes. 2002 Aug;51(8):2363-8. Adv Sci (Weinh). 2024 Jul 5:e2403451.\|Virol J. 2021 Sep 28;18(1):196.\|Biochem Pharmacol. 6 August 2022, 115198.\|EBioMedicine. 2022 Jul 28;82:104181.\|Research Square Print. December 19th, 2022.
Smiles	FC(C1=CC(CC(NCCOC(C2=CC=CC=C2)=O)C)=CC=C1)(F)F.[H]Cl
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	JP-992 (hydrochloride)
Shipping Condition	Room temperature
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	COVID-19-immunoregulation
Manufacturer - Targets	Orphan Receptor
Shipping Temperature	Room Temperature
Storage Conditions	4°C (Powder, sealed storage, away from moisture)
Molecular Weight	387.82
Product Description	Benfluorex hydrochloride (JP-992 hydrochloride) is a hepatic nuclear factor 4 alpha (HNF4α) activator.
Manufacturer - Research Area	Metabolic Disease; Cardiovascular Disease
Solubility	DMSO: ≥ 100 mg/mL\|H2O: 2.27 mg/mL (ultrasonic; warming; heat to 60°C)
Manufacturer - Pathway	GPCR/G Protein
Clinical information	Launched

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HY-B1058-10mM-safety-datasheet.pdf