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Cetrimonium (bromide)

Cetrimonium (bromide)

Item no.	HY-B1260-10mM
Manufacturer	MedChem Express
CASRN	57-09-0
Amount	10 mM/1 mL
Quantity options	100 mg 10 mM/1 mL
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	98.0
Citations	[1]Wu T K, et al. Cetrimonium bromide inhibits cell migration and invasion of human hepatic SK-HEP-1 cells through modulating the canonical and non-canonical TGF-β signaling pathways [J]. Anticancer research, 2019, 39(7): 3621-3631.\|[2]Ito E, et al. Potential use of cetrimonium bromide as an apoptosis-promoting anticancer agent for head and neck cancer [J]. Molecular pharmacology, 2009, 76(5): 969-983.\|[3]Isomaa B, et al. The subacute and chronic toxicity of cetyltrimethylammonium bromide (CTAB), a cationic surfactant, in the rat [J]. Archives of toxicology, 1976, 35: 91-96.\|[4]Allen G C, et al. A modified protocol for rapid DNA isolation from plant tissues using cetyltrimethylammonium bromide [J]. Nature protocols, 2006, 1(5): 2320-2325.
Smiles	CCCCCCCCCCCCCCCC[N+](C)(C)C.[Br-]
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	CTAB,Cetyltrimethylammonium (bromide),Hexadecyltrimethylammonium (bromide)
Shipping Condition	Room temperature
Available
Manufacturer - Type	Reference compound
Manufacturer - Targets	Apoptosis; Biochemical Assay Reagents; MMP; TGF-β Receptor
Shipping Temperature	Room Temperature
Storage Conditions	4°C (Powder, sealed storage, away from moisture and light)
Molecular Weight	364.45
Product Description	Cetrimonium bromide (CTAB), a quaternary ammonium, is an orally active cationic surfaetant. Cetrimonium bromide has toxicity and anticancer effect. Cetrimonium bromide inhibits cell migration and invasion through modulating the canonical and non-canonical TGF-β signaling pathways. Cetrimonium bromide can be used for DNA extraction[1][2][3][4].
Manufacturer - Research Area	Cancer
Solubility	DMSO: 10 mg/mL (ultrasonic)\|H2O: 4.55 mg/mL (ultrasonic)
Manufacturer - Pathway	Apoptosis; Metabolic Enzyme/Protease; Others; TGF-beta/Smad
Isoform	MMP-2; MMP-9
Clinical information	No Development Reported

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HY-B1260-10mM-safety-datasheet.pdf