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Desipramine (hydrochloride)

Desipramine (hydrochloride)

Item no.	HY-B1272-100mg
Manufacturer	MedChem Express
CASRN	58-28-6
Amount	100 mg
Quantity options	100 mg 10 mM/1 mL 1 g 500 mg 50 mg
Category	Oncology Neuroscience Molecular Targets for Neuroscience Neural Signaling Inhibitors & Compound Libraries Small Molecules By Organ Brain Cancer
Type	Inhibitors
Specific against	other
Purity	99.92
Citations	[1]Torres GE, et al. Plasma membrane monoamine transporters: structure, regulation and function. Nat Rev Neurosci. 2003 Jan;4(1):13-25.\|[2]Zhao Z, et al. Norepinephrine transporter regulation mediates the long-term behavioral effects of the antidepressant desipramine. Neuropsychopharmacology. 2008 Dec;33(13):3190-200. Biochim Biophys Acta Mol Basis Dis. 2023 Mar 28;1869(5):166700.\|Br J Pharmacol. 2024 Sep 5.\|Glia. 2022 Jul 1.\|Inflammation. 2021 Mar 4.\|J Parkinson Dis. 2020;10(2):523-542.\|Neural Regen Res. 2021;16:1660-70.\|Neuroscience. 2024 Feb 8:542:11-20.\|Neurotoxicology. 2022 Oct 6;S0161-813X(22)00156-5.\|Parkinsons Dis-us. 2022.\|Pharmaceutics. 2022, 14(8), 1523.\|Sci Total Environ. 2024 Mar 1:923:171405.\|Research Square Print. 2023 Feb 23.
Smiles	CNCCCN1C2=CC=CC=C2CCC3=CC=CC=C31.[H]Cl
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	58-28-6
Shipping Condition	Room temperature
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	Cancer-programmed cell death
Manufacturer - Targets	Dopamine Transporter; Serotonin Transporter
Shipping Temperature	Room Temperature
Storage Conditions	4°C (Powder, sealed storage, away from moisture)
Molecular Weight	302.84
Product Description	Desipramine hydrochloride is an inhibitor of norepinephrine transporter (NET), 5-HT transporter (SERT) and dopamine transporter (DAT) with Kis of 4, 61 and 78, 720 nM, respectively.
Manufacturer - Research Area	Neurological Disease; Cancer
Solubility	DMSO: ≥ 100 mg/mL\|H2O: 100 mg/mL (ultrasonic)
Manufacturer - Pathway	Neuronal Signaling
Clinical information	Launched

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HY-B1272-100mg-safety-datasheet.pdf