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Homatropine (methylbromide)

Homatropine (methylbromide)

Item no.	HY-B1388-100mg
Manufacturer	MedChem Express
CASRN	80-49-9
Amount	100 mg
Quantity options	100 mg 10 mM/1 mL 200 mg 500 mg 50 mg
Category	Oncology Inhibitors & Compound Libraries Small Molecules By Organ Skin Cancer
Type	Inhibitors
Specific against	other
Purity	98.0
Citations	[1]Sim MK et al. Muscarinic receptors in the aortae of normo- and hypertensive rats: a binding study. Clin Exp Hypertens. 1993 Mar;15(2):409-21.\|[2]Bryant SM et al. Intramuscular ophthalmic homatropine vs. atropine to prevent lethality in rates with dichlorvos poisoning. J Med Toxicol. 2006 Dec;2(4):156-9.\|[3]Leung E et al. Modification by hexamethonium of the muscarinic receptors blocking activity of pancuronium and homatropine in isolated tissues of the guinea-pig. Eur J Pharmacol. 1982 May 7;80(1):11-7.
Smiles	C[N+]1([C@@H]2C[C@@H](OC(C(O)C3=CC=CC=C3)=O)C[C@H]1CC2)C.[Br-]
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	Homatropine methobromide
Shipping Condition	Room temperature
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	Neuroscience-Neuromodulation
Manufacturer - Targets	mAChR
Shipping Temperature	Room Temperature
Storage Conditions	4°C (Powder, sealed storage, away from moisture)
Molecular Weight	370.28
Product Description	Homatropine methylbromide (Homatropine methobromide) is muscarinic AChR antagonist, inhibits endothelial and smooth muscle muscarinic receptors of WKY-E and SHR-E with IC50 of 162.5 nM and 170.3 nM, respectively.
Manufacturer - Research Area	Neurological Disease
Solubility	DMSO: ≥ 31 mg/mL\|H2O: ≥ 100 mg/mL
Manufacturer - Pathway	GPCR/G Protein; Neuronal Signaling
Clinical information	Launched

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HY-B1388-100mg-safety-datasheet.pdf