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Nifuroxazide

Nifuroxazide

Item no.	HY-B1436-200mg
Manufacturer	MedChem Express
CASRN	965-52-6
Amount	200 mg
Quantity options	10 mM/1 mL 200 mg 500 mg
Category	Oncology Neuroscience Neural Lineage Markers Neural Transcription Factors Inhibitors & Compound Libraries Small Molecules By Organ Colorectal Cancer Heart & Blood Cancer
Type	Inhibitors
Specific against	other
Purity	99.90
Citations	[1]Nelson EA, et al. Nifuroxazide inhibits survival of multiple myeloma cells by directly inhibiting STAT3. Blood. 2008 Dec 15;112(13):5095-102.\|[2]Zhu Y, et al. Nifuroxazide exerts potent anti-tumor and anti-metastasis activity in melanoma. Sci Rep. 2016 Feb 2;6:20253.
Smiles	O=C(N/N=C/C1=CC=C([N+]([O-])=O)O1)C2=CC=C(O)C=C2
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	965-52-6
Shipping Condition	Room temperature
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	Cancer-Kinase/protease
Manufacturer - Targets	Antibiotic; Bacterial; STAT
Shipping Temperature	Room Temperature
Storage Conditions	-20°C, 3 years; 4°C, 2 years (Powder)
Molecular Weight	275.22
Product Description	Nifuroxazide is an effective inhibitor of STAT3, also exerts potent anti-tumor and anti-metastasis activity. Nifuroxazide is an orally active nitrofuran antibiotic.
Manufacturer - Research Area	Cancer; Infection
Solubility	DMSO: ≥ 155 mg/mL
Manufacturer - Pathway	Anti-infection; JAK/STAT Signaling; Stem Cell/Wnt
Isoform	STAT3
Clinical information	Launched

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HY-B1436-200mg-safety-datasheet.pdf