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γ-Oryzanol

γ-Oryzanol

Item no.	HY-B2194-10mM
Manufacturer	MedChem Express
CASRN	11042-64-1
Amount	10 mM/1 mL
Quantity options	10 mM/1 mL 1 g 500 mg
Category	Neuroscience Neural Epigenetics Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	99.66
Citations	[1]Kozuka C, et al. Impact of brown rice-specific γ-oryzanol on epigenetic modulation of dopamine D2 receptors in brain striatum in high-fat-diet-induced obesity in mice. Diabetologia. 2017 Aug;60(8):1502-1511.
Smiles	[g-Oryzanol]
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	11042-64-1
Shipping Condition	Room temperature
Available
Manufacturer - Type	Natural Products
Manufacturer - Applications	Cancer-programmed cell death
Manufacturer - Targets	DNA Methyltransferase
Shipping Temperature	Room Temperature
Storage Conditions	-20°C, 3 years; 4°C, 2 years (Powder)
Molecular Weight	593.85 (average)
Product Description	γ-Oryzanol is a potent DNA methyltransferases (DNMTs) inhibitor in the striatum of mice. γ-Oryzanol significantly inhibits the activities of DNMT1 (IC50=3.2 μM), DNMT3a (IC50=22.3 μM).
Manufacturer - Research Area	Metabolic Disease; Cancer
Solubility	DMSO: 12.5 mg/mL (ultrasonic)
Manufacturer - Pathway	Epigenetics
Isoform	DNMT1; DNMT3
Clinical information	Launched

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HY-B2194-10mM-safety-datasheet.pdf